As a prolific singer, songwriter, dancer and bandleader, Brown was a pivotal force in the music industry. He left his mark on numerous artists. Brown's music also left its mark on the rhythms of African popular music, such as afrobeat, jùjú and mbalax, and provided a template for go-go music.

Brown began his professional music career in 1956 and rose to fame during the late 1950s and early 1960s on the strength of his thrilling live performances and string of smash hits. In spite of various personal problems and setbacks he continued to score hits in every decade through the 1980s. In addition to his acclaim in music, Brown was also a presence in American political affairs during the 1960s and 1970s.

Brown was recognized by numerous titles, including Soul Brother Number One, Sex Machine, Mr. Dynamite, The Hardest Working Man in Show Business, The King of Funk, Minister of The New New Super Heavy Funk, Mr. Please Please Please Please Her, I Feel Good, and foremost The Godfather of Soul. In the song "Sweet Soul Music" by Arthur Conley, he is described as the King of Soul.

James Brown was born to Susie (née Behlings) and Joseph ("Joe") James Gardner (who changed his surname to Brown after Mattie Brown who raised him). Although Brown was to be named after his father, his name was mistakenly reversed on his birth certificate, and instead became James Joseph Brown, Jr. As a young child, Brown was called Junior. When he later lived with his aunt and cousin, he was called Little Junior since his cousin's nickname was also Junior. James Brown is African American with Native American, specifically Apache, descent through his father, and Asian ancestry.

Brown and his family lived in extreme poverty. When Brown was two years old, his parents separated after his mother left his father for another man. After his mother abandoned the family, Brown continued to live with his father and his live-in girlfriends until he was six years old. After that time, Brown and his father moved to Augusta, Georgia.

His father sent him to live with an aunt, who ran a house of prostitution. Even though Brown lived with relatives, he spent long stretches of time on his own, hanging out on the streets and hustling to get by. Brown managed to stay in school until he dropped out in the seventh grade.

During his childhood, Brown earned money shining shoes, sweeping out stores, selling and trading in old stamps, washing cars and dishes and singing in talent contests. Brown also performed buck dances for change to entertain troops from Camp Gordon at the start of World War II as their convoys traveled over a canal bridge near his aunt's house. Between earning money from these adventures, Brown taught himself to play a harmonica given to him by his father. He learned to play some guitar from Tampa Red (who was "dating" one of the girls from his aunt's house), in addition to learning to play piano and drums from others. Brown was inspired to become an entertainer after watching Louis Jordan, a popular jazz and R&B performer during the 1940s, and His Tympany Five in a short film performing "Caldonia".

As an adult, Brown legally changed his name to remove the "Jr." designation. In his spare time, Brown spent time practicing his various skills in Augusta-area stalls and committing petty crimes. At the age of sixteen, he was convicted of armed robbery and sent to a juvenile detention center upstate in Toccoa in 1949.

While Brown was in reform school, he became acquainted with Bobby Byrd, who first saw Brown perform in prison. Byrd watched and admired Brown's ability to sing and perform. Byrd's family helped Brown secure an early release after serving three years of his sentence. The authorities agreed to release Brown on the condition that he would get a job and not return to Augusta or Richmond County. After stints as a boxer and baseball pitcher in semi-professional baseball (a career move ended by a leg injury), Brown turned his energy toward music.

Brown's career spanned decades, and profoundly influenced the development of many different musical genres. Brown moves on a continuum of blues and gospel-based forms and styles to a profoundly Africanised approach to music making. Brown performed in concerts, first making his rounds across the "chitlin' circuit", and then across the country and later around the world, along with appearing in shows on television and in movies. Although he contributed much to the music world through his hitmaking, Brown held the record as the artist who charted the most singles on the Billboard Hot 100 without ever hitting number one on that chart.